The self-learning AI releases the NFL against the spread, over-under and money line picks for every game of Week 6, 2024

The New Orleans Saints will be without starting quarterback Derek Carr (oblique) on Sunday when they host the Tampa Bay Buccaneers in the NFL’s Week 6 schedule. Head coach Dennis Allen named rookie Spencer Rattler the starter over Jake Haener, although the latter was the primary backup in Weeks 1–5. Carr’s injury caused a shift in the NFL odds in Week 6, as Tampa Bay went from a 2.5-point underdog to a 3.5-point favorite. The Buccaneers have a significant rest advantage after playing in Week 5 on Thursday. So should you bet on Tampa in the Week 6 NFL spreads?

Injuries are an important factor to consider each week, along with factors such as spot scheduling, weather and line movement. There are six NFL lines within a field goal in Week 6, while Philadelphia (-8.5 vs. Cleveland) is the only team with an advantage by more than one score. Before making NFL picks for Week 6, you need to compare the NFL using the spread, over-under and money line predictions from the self-learning SportsLine AI.

For each game, AI predictions and AI ratings are created by SportsLine’s data science team using state-of-the-art artificial intelligence and machine learning techniques. The AI ​​predictions are determined by statistically learning from each team’s historical data and then quantitatively assessing the strength of the opponent’s defense by assigning a numerical value of 100, called the matchup score.

Once a prediction is formulated, the AI ​​assessment is created based on the prediction, matchup score and market opportunities. For example, you might see an A rating on an over bet if a team faces a weak defense, their prediction is off the line, and there are favorable odds.

Additionally, SportsLine AI is the first fully automated prediction model at SportsLine. It is continually updated with the latest data available and can help you spot the biggest variations in the rows. SportsLine’s AI PickBot has hit 128 4-star or better picks this season and a whopping 1,674 4.5- and 5-star prop picks last season. Anyone who has followed it is way up there.

For NFL betting in Week 6, the AI ​​PickBot evaluated the NFL odds and provided NFL betting predictions for all 14 games. Here you can only see the AI ​​predictions for the Week 6 NFL schedule.

The best AI picks of Week 6 in the NFL

After analyzing every game in Week 6, the AI ​​PickBot says the Broncos are covering as 3-point home underdogs against the Chargers in a game with the lowest over-under of the week, 35.5. Denver has quietly found a way to win over the past month, riding a three-game winning streak that includes double-digit victories over the Buccaneers and Raiders. The Broncos rank eighth in combined offensive and defensive success rate through their first five games, while the Chargers barely crack the top 20.

Denver’s rookie quarterback Bo Nix may not be leading an explosive offense, but he has played efficiently and avoided mistakes. The Broncos have also held four straight opponents under 20 points, and the Chargers’ offense ranks 31st in success rate through four games. The AI ​​PickBot expects Denver to pick up its fourth straight win as the Broncos with win overall with an average final score of 20-18. For more Week 6 football predictions and football picks, stay tuned to SportsLine.

How to make NFL picks for Week 6

Additionally, the AI ​​PickBot generated 14 additional A-rated picks for Week 6, including two with the coveted A+ grade. You need to check out AI PickBot’s NFL picks before making your own Week 6 NFL bets. You can only see them at SportsLine.

Who will win and cover every NFL game of Week 6 and which A+ picks should you target now? Visit SportsLine now to see the best NFL picks against the spread, over-under and on the money line, all from the all-new SportsLine AI PickBot, which made 128 top picks this season.